CALL US AT: (877) 838.BABY


Archive for the ‘Frank Palopoli’ tag

Reflecting on the Contribution of Clomid® Chemist, Frank Palopoli

By David Kreiner MD

August 18th, 2016 at 9:50 am

 

image credit: nenetus/freedigitalphotos.net


I was cooling off in my community pool and a former patient recognized me and proudly  showed off her 13 year old daughter…”just Clomid® right?”, I asked, a trite too brash.  “Yes, and insemination after a couple of failed attempts,” she replied.

I sometimes assume if a patient doesn’t have to do IVF to conceive that they have not sufficiently suffered the infertility rites of passage.  Shame on me…for someone facing the challenge of conceiving, the pain can be most severe and if solved with fertility pills—Clomid®–then it is just as miraculous a cure as the newer technologic marvel of IVF.

I have experienced in my 31 years as a reproductive endocrinologist specializing in fertility several hundred such successes and babies born from this highly successful fertility pill that was developed by a team in the 1950’s led by Frank Palopoli who died last week at the age of 94.

Clomiphene®, the generic form of the estrogen receptor inhibitor that came on the market in 1967, works by blocking the negative feedback of estrogen resulting in an increase of pituitary hormones, FSH and LH which in turn stimulates the ovaries to ovulate.

Clomid® may be used by itself or augmented with injections of LH and/or FSH as well as HCG used as a trigger for ovulation when the ovarian follicles stimulated by Clomid® have reached maturity.  The pills are usually taken in the beginning of the cycle for five days and the response carefully monitored with serum estradiol and LH levels as well as follicular ultrasounds.

As tens of millions of babies have been born since Mr. Palopoli developed Clomid® we in the field and those who have reaped the rewards of this medication owe him a tremendous debt of gratitude.

* * ** * * *** *

Did Clomid® play a part in your fertility journey?

 

no comments


The Fertility Daily Blog by Long Island IVF
© Copyright 2010-2012